Alpha Phi (ΑΦ, also known as A-Phi) is a national women's fraternity founded at Syracuse University in Syracuse, New York on September 18, 1872, it is the fourth Greek-letter organization founded for women, and the first women's fraternity founded in the northeast.

At the time of the founding there were only 666 women attending Syracuse; ten of them eventually formed of Alpha Phi to found an organization "on the principles of the promotion of growth in character; unity of feeling, sisterly affection, and social communion among the members."Although the actual founding date is September 18, 1872, Alpha Phi has been celebrating their Founders Day on October 10 since 1902, since many colleges and universities were not open for classes in mid-September at that time. Alpha Phi considers itself a women's fraternity because its founding date predates the invention of the word "sorority".

The Beta Sigma Chapter was founded at the University of Utah in 2012.